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Lenalidomide may delay the onset of bone and other myeloma-related organ damage in patients with smoldering multiple myeloma, according to a study published in the Journal of Clinical Oncology. “Our findings are in line with a smaller trial in 2015 by researchers in Spain,” said S. Vincent...
The US Food and Drug Administration (FDA) has approved daratumumab (Darzalex) in combination with bortezomib, thalidomide, and dexamethasone in patients newly diagnosed with multiple myeloma who are eligible for autologous stem cell transplant (ASCT). Efficacy was investigated in CASSIOPEIA, an...
Combining selinexor with dexamethasone is effective for patients with treatment-resistant multiple myeloma, according to a study published in The New England Journal of Medicine. Proteins and messenger RNAs play an important part of cancer cell growth, and selinexor has an unprecedented mechanism...
Researchers have linked inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents, according to a study published in JAMA Oncology. “The BRCA family of genes are known to be linked to risk for breast and ovarian cancer as well as...
Individuals with low- or intermediate-risk monoclonal gammopathy of undetermined significance (MGUS) can convert to high-risk MGUS and progress to multiple myeloma within a 5-year window, according to a study published in JAMA Oncology. The findings support recommendations for annual blood tests...

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