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Dose-adjusted etoposide, doxorubicin, cyclophosphamide, vincristine, prednisone, and rituximab (DA-EPOCH-R), which is less toxic than standard dose-intensive chemotherapy, was found to be highly effective for adults with Burkitt lymphoma across all age groups and independent of HIV status,...
The US Food and Drug Administration (FDA) approved daratumumab and hyaluronidase-fihj (Darzalex Faspro) for adult patients with newly diagnosed or relapsed/refractory multiple myeloma. This new product allows for subcutaneous dosing of daratumumab. Daratumumab and hyaluronidase-fihj is approved...
KTE-X19, an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, induced durable remissions in a majority of patients with relapsed or refractory mantle cell lymphoma, according to a study published in The New England Journal of Medicine. Patients in the phase 2, multicentre ZUMA-2 study had...
The US Food and Drug Administration (FDA) has approved isatuximab-irfc (Sarclisa), in combination with pomalidomide and dexamethasone, for the treatment of adult patients with multiple myeloma who have received at least 2 prior therapies including lenalidomide and a proteasome inhibitor....
Treatment with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK)-cell therapy targeting CD19 resulted in clinical responses in a majority of patients with relapsed or refractory non-Hodgkin’s lymphoma (NHL) and chronic lymphocytic leukemia (CLL), with no major toxicities...

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